NALOXONE AUTO-INJECTOR is an opioid antagonist indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression in adults and pediatric patients.
NALOXONE AUTO-INJECTOR is intended for immediate administration as emergency therapy in settings where opioids may be present.
NALOXONE AUTO-INJECTOR is not a substitute for emergency medical care.
How to use NALOXONE AUTO-INJECTOR
Pull NALOXONE AUTO-INJECTOR from the outer case.
Do not go to Step 2 (Do not remove the Red safety guard) until you are ready to use NALOXONE AUTO-INJECTOR. If you are not ready to use NALOXONE AUTO-INJECTOR, put it back in the outer case for later use.
Pull off the Red safety guard.
To reduce the chance of an accidental injection, do not touch the Black base of the auto-injector, which is where the needle comes out. If an accidental injection happens, get medical help right away.
Note: The Red safety guard is made to fit tightly. Pull firmly to remove. Do not replace the Red safety guard after it is removed.
Place the Black end of NALOXONE AUTO-INJECTOR against the outer thigh, through clothing, if needed. Press firmly and hold in place for 5 seconds. If you give NALOXONE AUTO-INJECTOR to an infant less than 1 year old, pinch the middle of the outer thigh before you give NALOXONE AUTO-INJECTOR and continue to pinch while you give NALOXONE AUTO-INJECTOR.
Note: NALOXONE AUTO-INJECTOR makes a distinct sound (click and hiss) when it is pressed against the thigh. This is normal and means that NALOXONE AUTO-INJECTOR is working correctly. Keep NALOXONE AUTO-INJECTOR firmly pressed on the thigh for 5 seconds after you hear the click and hiss sound. The needle will inject and then retract back up into the NALOXONE AUTO-INJECTOR and is not visible after use.
After using NALOXONE AUTO-INJECTOR, get emergency medical help right away. If symptoms return after an injection with NALOXONE AUTO-INJECTOR, an additional injection using another NALOXONE AUTO-INJECTOR may be needed. Give additional injections using a new NALOXONE AUTO-INJECTOR every 2 to 3 minutes and continue to closely watch the person until emergency help is received. NALOXONE AUTO-INJECTOR does not take the place of emergency medical care.
NALOXONE AUTO-INJECTOR cannot be reused. After use, place the auto-injector back into its outer case. Do not replace the Red safety guard.
For more detailed information on how to use NALOXONE AUTO-INJECTOR, click here.
To report an adverse event or product complaint about EVZIO or the authorized generic NALOXONE AUTO-INJECTOR, please call 1-855-625-6966.