Use Cases
A Countermeasure to the Threat of Synthetic Opioids
Kaléo designed this device to be useful in protecting civilians and government employees who may come in contact with ultra-potent opioids in the fulfillment of their duties or during a mass casualty event. Naloxone Auto-Injector 10 mg can be administered through clothing, including personal protective equipment such as MOPP4. Removal of personal protective equipment is not required.
Usability and Simulated Real-World Use Scenarios
Two human factor validation studies were conducted to validate the user interface of Naloxone Auto-Injector 10 mg for law enforcement officers, emergency medical services personnel, and military personnel using simulated use scenarios and post-simulation interviews. Overall, all seventy-five participants were able to successfully deliver a simulated Naloxone Auto-Injector 10 mg dose to either a victim or themselves and answered all critical knowledge task questions correctly3.
Sixty Law Enforcement & Emergency Medical Services Personnel
Untrained participants – half of whom where experienced with a trainer for a similar autoinjector – were instructed to administer NAI 10 mg to an opioid overdose victim (manikin) in a simulated sports bar/recreational area.
The testing environment included variables aimed at inducing stress (e.g., low lighting, flashing disco lights, loud music, beeping that increased in frequency and loudness, live patron bystanders).
100% Completed a Simulation
Fifteen Military Personnel
A week after instructor-led training on NAI 10 mg use, participants were asked to don MOPP4 and administer NAI 10 mg to an unconscious soldier (manakin also wearing PPE) and themselves (due to a breach in PPE) in a simulated scenario where a high-potency opioid had been released in a populated area.
In addition to the challenges inherent with MOPP Level 4 (e.g., impaired dexterity, tactility, visibility), environmental challenges included emergency sirens/alarms, fog, darkness, flashing emergency lights, crowded space, multiple casualties, and beeping that increased in frequency/loudness.
100% Completed a Simulation
Limitations: These studies were sponsored by Kaléo. As this was a simulated use scenario, participants may not have experienced the same level of stress that they might experience during an actual event.